Generic Name: Amlodipine
Norvasc is the brand name for amlodipine, a prescription medicine commonly used to treat high blood pressure (hypertension) and certain types of angina (chest pain). It belongs to a group of medicines called calcium channel blockers (CCBs).
Amlodipine works mainly by relaxing and widening blood vessels. This allows blood to flow more easily and reduces the pressure against the walls of the arteries. As a result, the heart does not have to work as hard to pump blood around the body.
Norvasc is usually taken once daily and can be used alone or alongside other blood pressure medicines. Because hypertension often does not cause noticeable symptoms, regular treatment is important even when a person feels completely well.
Amlodipine may also be prescribed for certain forms of coronary artery disease. It can help prevent episodes of angina, although it is not intended to provide immediate relief during an acute angina attack.
Norvasc blocks calcium from entering certain muscle cells in the walls of blood vessels. Calcium is involved in muscle contraction, so reducing calcium entry allows the arteries to relax.
This results in:
Relaxation of blood vessels
Lower blood pressure
Improved blood flow
Reduced workload on the heart
Reduced frequency of some types of angina
Amlodipine has a relatively long duration of action, which allows convenient once-daily dosing for many patients.
Norvasc is widely used to control hypertension. It may be prescribed by itself or combined with medicines such as ACE inhibitors, ARBs, beta blockers or diuretics when additional blood pressure control is needed.
Consistent blood pressure control can reduce the long-term risk of stroke, heart attack, heart failure and kidney complications.
Norvasc controls high blood pressure but does not permanently cure it. Treatment often needs to continue for a long period.
Do not stop amlodipine without speaking with your healthcare professional, even if your blood pressure improves.
The most common use of Norvasc is the treatment of hypertension.
By relaxing blood vessels, amlodipine reduces resistance to blood flow and lowers blood pressure.
Keeping blood pressure within the recommended range can help protect the heart, brain, kidneys and blood vessels.
Norvasc may be prescribed to help prevent stable angina, a type of chest pain that occurs when the heart muscle does not receive enough oxygen-rich blood.
It may reduce the frequency of angina episodes by improving blood flow and decreasing the workload of the heart.
Amlodipine can also be used for vasospastic or Prinzmetal angina, in which coronary arteries temporarily narrow or spasm.
By relaxing blood vessels, amlodipine can help prevent these episodes.
Some patients with coronary artery disease may receive amlodipine to help manage associated high blood pressure or angina.
The treatment plan depends on the person's cardiovascular condition and other medicines.
Norvasc can be combined with other medicines when one treatment does not provide enough blood pressure control.
Combination therapy is common in people with moderate or difficult-to-control hypertension.
Norvasc is generally used for ongoing blood pressure control and prevention of angina rather than as an emergency medicine for sudden chest pain.
If chest pain is new, severe, persistent or associated with sweating, shortness of breath, fainting or pain spreading to the arm or jaw, seek emergency medical care.
Most people tolerate amlodipine well, but side effects can occur.
Peripheral edema, particularly swelling around the ankles and feet, is one of the more common side effects of amlodipine.
The swelling occurs because blood vessels widen and fluid can move into surrounding tissues.
Inform your doctor if swelling becomes severe or uncomfortable.
Headache may occur, particularly when treatment is first started.
It often improves as the body adjusts to the medicine.
Amlodipine can sometimes cause dizziness, especially if blood pressure becomes lower than expected.
Stand up slowly from sitting or lying positions if you feel lightheaded.
Some people may experience facial warmth or flushing because of blood vessel relaxation.
This is usually mild but should be reported if it is persistent or severe.
Feeling tired or lacking energy can occur in some patients.
If fatigue interferes with normal activities, discuss it with your healthcare professional.
Some patients may notice a faster heartbeat or a sensation of their heart beating strongly.
Persistent or severe palpitations should be medically evaluated.
Nausea or mild digestive discomfort can occasionally occur.
Persistent vomiting or severe stomach symptoms should be assessed.
Some patients may experience abdominal pain or discomfort while taking amlodipine.
Discuss ongoing symptoms with your doctor.
Long-term use of calcium channel blockers can occasionally contribute to gum overgrowth.
Good oral hygiene and regular dental care can be helpful.
Although amlodipine is prescribed to lower high blood pressure, blood pressure can occasionally become too low.
Symptoms may include dizziness, weakness, blurred vision or fainting.
A serious allergic reaction is rare.
Emergency medical attention is needed if you experience difficulty breathing, swelling of the face or throat, severe rash or fainting.
The appropriate Norvasc dose depends on the patient's age, medical condition, blood pressure, response to treatment and other medicines.
Amlodipine tablets are commonly available in 2.5 mg, 5 mg and 10 mg strengths.
For many adults, the usual starting dose is 5 mg once daily.
Depending on the response, the doctor may increase the dose to 10 mg once daily.
Some patients may start at 2.5 mg, particularly older adults or people who may be more sensitive to blood pressure changes.
For angina, the usual adult dose is commonly 5 mg to 10 mg once daily, depending on the individual patient.
The exact dose should be determined by the prescribing healthcare professional.
Older adults may be more sensitive to blood pressure changes.
A lower starting dose may be considered, particularly when other medicines or health conditions increase the risk of dizziness or low blood pressure.
Amlodipine may be used in certain children with hypertension.
For children aged 6 years and older, dosing is typically individualized, and the commonly recommended starting dose is 2.5 mg once daily, with adjustment according to response.
Pediatric treatment should always be supervised by a healthcare professional.
People with liver impairment may require careful dose selection because amlodipine can remain in the body longer.
Tell your doctor if you have liver disease.
Amlodipine is generally not significantly affected by kidney impairment, but people with kidney disease should still inform their doctor about their condition.
Norvasc is usually taken once daily, with or without food.
Try to take it at approximately the same time every day.
Swallow the tablet with water according to the prescription instructions.
If you forget a dose, take it when you remember unless it is nearly time for your next dose.
If the next dose is close, skip the missed dose and return to your normal schedule.
Do not take two doses together.
Taking too much amlodipine can cause excessive low blood pressure, dizziness, fainting or a rapid heartbeat.
A suspected overdose requires prompt medical assessment.
Amlodipine can be combined safely with many medicines, but interactions are possible.
Tell your doctor or pharmacist about all prescription medicines, over-the-counter products and supplements you use.
Combining amlodipine with other antihypertensive medicines can produce a stronger blood-pressure-lowering effect.
This combination may be appropriate but should be monitored by a healthcare professional.
Amlodipine is sometimes prescribed alongside beta blockers.
Doctors may use the combination for hypertension or certain types of heart disease.
Amlodipine can increase exposure to simvastatin.
When these medicines are used together, the simvastatin dose may need to be limited according to prescribing guidance.
Some medicines that affect liver enzymes can increase amlodipine levels.
Tell your doctor if you are taking antifungal or other medicines that may affect drug metabolism.
Grapefruit is not generally considered to have the same clinically important interaction with amlodipine as it does with some other calcium channel blockers, but patients should still follow their healthcare professional's advice regarding diet and medicines.
Amlodipine may be used during pregnancy when a doctor determines that treatment is appropriate.
High blood pressure during pregnancy can itself be dangerous, so medication decisions should be made with a healthcare professional.
If you are pregnant or planning pregnancy, tell your doctor before starting or changing Norvasc.
Amlodipine passes into breast milk in small amounts.
Available information suggests that it can sometimes be used during breastfeeding when clinically appropriate, but the decision should be made with a healthcare professional.
Amlodipine begins lowering blood pressure after treatment starts, but its full effect may take several days to a couple of weeks to become clear.
Because it has a long duration of action, it is usually taken once daily.
Do not increase the dose simply because you do not notice an immediate change in blood pressure.
A heart-healthy diet can support blood pressure control.
Reducing excessive salt intake and eating appropriate amounts of vegetables, fruits, whole grains and other nutritious foods may help maintain healthy blood pressure.
Regular physical activity can help improve blood pressure and cardiovascular fitness.
Choose activities suitable for your health and fitness level.
If you have significant heart disease or other medical problems, ask your healthcare professional about an appropriate exercise plan.
Many people use amlodipine for several years to control hypertension or prevent angina.
Stopping the medicine without medical advice may allow blood pressure to rise again or angina symptoms to return.
Regular follow-up helps ensure the treatment remains appropriate.
Your healthcare professional may monitor:
Blood pressure
Heart rate
Ankle or leg swelling
Dizziness or fainting
Angina symptoms
Overall cardiovascular health
Regular monitoring helps identify whether the dose needs adjustment.
Norvasc can help prevent certain types of angina, but it is not intended to provide immediate relief from an acute attack of chest pain.
If you experience sudden or severe chest pain, especially with shortness of breath, sweating, nausea, fainting or pain spreading to the arm, shoulder, back or jaw, seek emergency medical help.
Contact your doctor if you develop severe swelling, persistent dizziness, fainting, worsening chest pain or significant changes in heartbeat.
Seek emergency care for severe chest pain, difficulty breathing, facial or throat swelling or other signs of a serious allergic reaction.
Take Norvasc exactly as prescribed and do not increase, decrease or stop the medicine without medical advice. Tell your healthcare professional if you have liver disease, heart problems, very low blood pressure or are taking other blood pressure or cholesterol medicines. If ankle swelling becomes persistent or severe, discuss it with your doctor.
Note: This information is for general educational and SEO purposes and does not replace advice from a qualified doctor or pharmacist. Norvasc (amlodipine) is a prescription medicine, and the appropriate dose depends on the patient's age, medical condition, blood pressure, response to treatment and other medicines.
Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider. In an emergency, call emergency services immediately.